损失 (sǔn shī) is a broad term for 'loss' or 'damage' — it can refer to losing something physically, financially, or abstractly. It differs from 损伤 (sǔn shāng), which emphasizes physical harm or injury, and from 亏损 (kuī sǔn), which is specifically a financial deficit in business. 失落 (shī luò) is more about losing an object or feeling emotionally lost.